Nitrosourea derivative and process for preparing same

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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536 41, C07H 1102

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active

044725736

ABSTRACT:
A nitrosourea compound of the formula: ##STR1## wherein R.sup.1 is lower alkyl and R.sup.2 is lower alkyl or lower alkoxy-lower alkyl, which may be prepared by nitrosation of a compound of the formula: ##STR2## wherein R.sup.1 and R.sup.2 are the same as defined above. Said nitrosourea compound is useful as an anti-tumor or anti-leukemic agent.

REFERENCES:
patent: 3767640 (1973-10-01), Suami et al.
patent: 4086415 (1978-04-01), Suami et al.
patent: 4156777 (1979-05-01), Kimura
patent: 4182757 (1980-01-01), Tsujihara et al.
patent: 4273766 (1981-06-01), Stanek
Johnston et al., Journ. Med. Chem. 18 (1), p. 104 (1975).

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