Nitroso esters of beta-oxo-amides and aryl propionic acid deriva

Details Nitroso esters of beta-oxo-amides and aryl propionic acid deriva Nitroso esters of beta-oxo-amides and aryl propionic acid deriva

1999-01-22

2000-03-28

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ortho-hydroxybenzoic acid or derivative doai

514166, 514364, 514413, 514513, 514539, 514619, 514622, 548126, 548453, 558256, 560 47, 560 48, 560 59, 560 71, 564163, 564177, A61K 31407, A61K 314245, A61K 31245, C07D48704, C07D27104

Patent

active

060432322

ABSTRACT:
A compound comprising a non-steroidal antiinflammatory agent to which is directly or indirectly linked an NO group, a compound comprising an enolic anilide non-steroidal antiinflammatory agent to which is directly or indirectly linked an NO.sub.2 group, a pharmaceutical composition including the compounds and methods of treatment of pain and/or inflammation using the compounds and compositions are disclosed. Also disclosed is a composition comprising a non-steroidal antiinflammatory agent and a compound that donates, transfers or releases nitric oxide.

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