Nitroimidazolyl pyrimidines

Details Nitroimidazolyl pyrimidines Nitroimidazolyl pyrimidines

1975-04-14

1976-06-29

Schenkman, Leonard

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602565R, 2603096, 2602564R, C07O23900

Patent

active

039667324

ABSTRACT:
Nitroimidazolyl pyrimidines of the formula ##SPC1##
And physiologically acceptable acid addition salts thereon wherein X is alkyl of 1-4 carbon atoms, R.sub.1 and R.sub.2 each are a hydrogen atom, alkyl of 1-4 carbon atoms, phenyl triflouromethyl or a monocyclic heterocyclic ring and R.sub.3 is a hydrogen atoms, alkyl of 1-4 carbon atoms, hydroxyalkoxy of 2-4 carbon atoms or an ester thereof of an alkanocarboxylic acid of 1-4 carbon atoms, oxoalkyl of 8-6 carbon atoms, or, when R.sub.1 or R.sub.2 is phenyl, alkylene having 1-2 carbon atoms in the chain joined to the 2-position of the phenyl ring possess trichomonicidal activity.

REFERENCES:
patent: 3880852 (1975-04-01), Cole et al.
Merck Inpex 8th Ed. p. 695 (1968).

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