Nitrogenous heterocyclic compounds, preparation thereof and...

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S300000

Reexamination Certificate

active

08063219

ABSTRACT:
The invention concerns nitrogenated heterocyclic compounds, their preparation and use as antibacterial drugs, compounds of general formula (I)wherein R1represents a (CH2)n-NHR2or (CH2)n-NHR radical, where R is a (C1-C6) alkyl and n is equal to 1 or 2;R2represents a hydrogen atom;R3and R4together form an aromatic nitrogenated heterocycle with 5 apexes with 1, 2 or 3 nitrogen atoms optionally substituted by one or several R′ groups, R′ being selected in the group composed of a hydrogen atom and alkyl radicals with 1 to 6 carbon atoms;in free form, as zwitterions, and in the form of salts of pharmaceutically acceptable inorganic or organic bases and acids.

REFERENCES:
Silverman, The Organic Chemistry of Drug Design and Drug Action, Academic Press (1992).
Written Opinion of the International Searching Authority, International Application No. PCT/FR2008/000509, date of mailing, Oct. 13, 2009 and attached English Translation.
Written Opinion of the International Searching Authority, International Application No. PCT/FR2008/000509, date of mailing, Nov. 3, 2009 and attached English Translation.

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