Nitrogen-substituted mevinic acid derivatives useful as HMG-CoA

Details Nitrogen-substituted mevinic acid derivatives useful as HMG-CoA Nitrogen-substituted mevinic acid derivatives useful as HMG-CoA

1992-10-09

1994-11-29

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514429, 514460, 514510, 548517, 548579, 549292, 560119, A61K 3140, A61K 31365, C07D30930, C07C 6974

Patent

active

053691237

ABSTRACT:
Novel nitrogen-substituted mevinic acid derivatives which inhibit the activity of HMG-CoA reductase. Pharmaceutical compositions, and methods of use for the treatment or prevention of hypercholesterolemia, atherosclerosis, hyperlipoproteinaemia and hyperlipidemia are provided, as are novel methods for preparation and intermediate compounds.

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