Nitrogen-containing silicone useful for compacting nucleic acid

Details Nitrogen-containing silicone useful for compacting nucleic acid Nitrogen-containing silicone useful for compacting nucleic acid

1999-04-05

2000-05-30

Ketter, James

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435458, 435459, 435470, 435471, C12Q 168

Patent

active

060689803

ABSTRACT:
The present invention relates to a method of transforming cells in which an appropriate quantity of nucleic acid fragments is introduced into the cells. The nucleic acid fragments are introduced in the form of a nucleic acid composition comprising a nitrogen-containing silicone, useful for compacting the nucleic acid fragments; the compositions comprise aggregates of nucleic acid fragments and silicones according to the invention.

REFERENCES:
patent: 5302523 (1994-04-01), Coffee et al.
Fang et al. (1998) Nucleic Acids Research 26:588.
Fromm et al. (1990) Bio/Technology 8:833.

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