Nitrogen-containing heterocyclic compounds, their...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C546S121000

Reexamination Certificate

active

08067435

ABSTRACT:
The invention relates to nitrogen-containing heterocyclic compounds of general formula (I)wherein:R1represents a (CH2)n—NH2radical, n being equal to 1 or 2;R2represents a hydrogen atom;R3and R4form together a nitrogen-containing heterocycle with aromaticity with 5 apices containing 1, 2 or 3 nitrogen atoms, substituted on this nitrogen atom or one of these nitrogen atoms with a (CH2)m—(C(O))p—R5group, m being equal to 0, 1, 2 or 3, p being equal to 0 or 1 and R5representing a hydroxy group, in which case p is equal to 1, or an amino, (C1-C6)alkyl or di-(C1-C6)alkyl amino, a nitrogen-containing heterocycle with aromaticity with 5 or 6 apices containing 1 or 2 nitrogen atoms and if necessary, an oxygen or sulfur atom;it being understood that when the sub-group (C(O))p—R5forms a carboxy, amino, (C1-C6) alkyl or di-(C1-C6) alkyl amino, group, m is different from 0 or 1;in free form or as zwitterions and salts with pharmaceutically acceptable mineral or organic bases and acids, to their preparation and to their use as antibacterial drugs.

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