Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2011-06-28
2011-06-28
Padmanabhan, Sreeni (Department: 1627)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S359000, C514S365000, C514S366000, C514S374000, C514S375000, C514S439000, C514S461000, C514S468000, C546S271400, C546S271100
Reexamination Certificate
active
07968572
ABSTRACT:
It is intended to provide a compound represented by the formula (I):wherein all the symbols are as defined in the description;which has a p38 MAP kinase inhibitory activity, a salt thereof, an N-oxide thereof, a solvate thereof, or a prodrug thereof. The compound of the invention is useful for preventing or treating a disease in which the abnormal production of a cytokine such as an inflammatory cytokine or a chemokine or overreaction to them is considered to be involved in the cause and aggravation of pathological conditions, in other words, an inflammatory disease, a respiratory disease, a cardiovascular disease, a central nervous system disease or the like, which is a cytokine-mediated disease.
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Hirosaki Tomomi
Nakai Hisao
Nakatani Shingo
Yamamoto Shingo
Javanmard Sahar
Ono Pharmaceuticals Co. Ltd.
Padmanabhan Sreeni
Sughrue & Mion, PLLC
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