Nitrogen-containing heterocyclic compound

Details Nitrogen-containing heterocyclic compound Nitrogen-containing heterocyclic compound

2006-04-19

2010-06-29

Anderson, Rebecca L (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C514S414000

Reexamination Certificate

active

07745641

ABSTRACT:
The present invention provides a nitrogen-containing heterocyclic compound represented by formula (I):{wherein W represents a nitrogen atom or —CH—;X represents —C(═O)— or —CHR4— (wherein R4represents a hydrogen atom, or the like};R1represents a group represented by the following formula:[wherein Q1represents a nitrogen atom or —CR8— (wherein R8represents a hydrogen atom, substituted or unsubstituted lower alkyl, or the like). Q2represents —NR15— (wherein R15represents a hydrogen atom, or the like) and R5and R6may be the same or different and each represents a hydrogen atom, substituted or unsubstituted lower alkyl, or the like]; andR2and R3may be the same or different and each represents a hydrogen atom, halogen, substituted or unsubstituted lower alkyl, or the like} or a pharmaceutically acceptable salt thereof, and the like.

REFERENCES:
patent: 5491144 (1996-02-01), Trinks et al.
patent: 5663336 (1997-09-01), Trinks et al.
patent: 2005/0026976 (2005-02-01), Curtin et al.
patent: 2005/0054670 (2005-03-01), Tegley et al.
patent: 2005/0101518 (2005-05-01), Solow-Cordero et al.
patent: 2005/0130943 (2005-06-01), Wallace et al.
patent: 2005/0182061 (2005-08-01), Green et al.
patent: 2005/0261298 (2005-11-01), Solow-Cordero et al.
patent: 2005/0267108 (2005-12-01), Hsieh et al.
patent: 2007/0032459 (2007-02-01), Solow-Cordero et al.
patent: 2 069 857 (1992-12-01), None
patent: 05-163240 (1993-06-01), None
patent: 5-163240 (1993-06-01), None
patent: 10-231285 (1998-09-01), None
patent: 2004/108672 (2004-12-01), None
patent: 2005/095341 (2005-10-01), None
patent: 2007/047646 (2007-04-01), None
Kubinyi (3D QSAR in Drug Design: Ligand-Protein Interactions and Molecular Similarity, vol. 2-3, Springer, 1998, 800 pages), TOC and pp. 243-244 provided.
Curtin, et al., “Isoindolinone ureas: a novel class of KDR kinase inhibitors”, Bioorganic & Medicinal Chemistry Letters, vol. 14, No. 17 (2004) 4505-09.
Takami, et al., “Design and synthesis of Rho kinase inhibitors (I)”, Bioorganic & Medicinal Chemistry Letters, vol. 12, No. 9 (2004) 2115-37.

Affiliated with

Also associated with

Rating

Nitrogen-containing heterocyclic compound does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Nitrogen-containing heterocyclic compound, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nitrogen-containing heterocyclic compound will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4188354