Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2007-02-06
2007-02-06
Habte, Kahsay (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C540S481000, C540S599000, C544S236000, C514S217060
Reexamination Certificate
active
11190859
ABSTRACT:
As a result of an effort made by us for the purpose of developing a therapeutic agent having a bone formation-stimulating effect by promoting the functions of osteoblasts, the present inventors discovered that a certain nitrogen-containing heterocyclic compound exhibits a potent bone formation-stimulating effect on the osteoblast and thus can serve as an excellent prophylactic or therapeutic agent against a metabolic bone disease, whereby establishing the present invention.Thus, the present invention provides a 3,6-disubstituted 1,2,4-triazolo[4,3-b]pyridazine compound or a pharmaceutically acceptable salt thereof as well as a pharmaceutical composition comprising such a compound and a pharmaceutically acceptable carrier, especially a bone-forming agent.
REFERENCES:
patent: 3957766 (1976-05-01), Berger et al.
patent: 2 161 586 (1971-12-01), None
patent: 2 161 587 (1971-12-01), None
patent: 2 215 999 (1972-04-01), None
patent: 2 113 438 (1972-09-01), None
patent: 2 254 873 (1972-11-01), None
patent: 2 261 693 (1972-12-01), None
patent: 24 44 322 (1974-09-01), None
patent: 1 277 754 (2003-01-01), None
patent: 50-58092 (1975-05-01), None
patent: WO 00/59484 (2000-10-01), None
patent: WO 01/83481 (2001-11-01), None
Legraverend et al. J. Heterocyclic Chem., 18, 893-898 (1981).
Parravicini et al., “Derivati Della 3-Idrazinopiridazina”,Farmaco. Ed. Sci., 34(4), 299-310 (1979).
Tabak et al., “Steric Effects in 1-Phenyl-5-substituted Pyrazoles”,Tetrahedron, 22(7), 2703-9 (1966).
Igarashi Susumu
Kanoh Hiroyuki
Kawano Noriyuki
Kobori Masato
Naito Ryo
Astellas Pharma Inc.
Habte Kahsay
LandOfFree
Nitrogen-containing heterocyclic compound does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Nitrogen-containing heterocyclic compound, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nitrogen-containing heterocyclic compound will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3819401