Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-07-11
2006-07-11
Saeed, Kamal A. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S307000, C514S314000, C546S118000, C546S121000, C546S122000, C546S144000, C546S167000
Reexamination Certificate
active
07074801
ABSTRACT:
The present invention discloses compounds and compositions of formula (I):having inhibitory activity on activation of STAT6, wherein X represents quinoline, isoquinoline, quinazoline or imidazopyridine; Y represents phenyl, piperazine, pyridine, thiophene, thiazole, oxathiazole or oxathiadiazole; and variables Z, n, R1, R2, R3and R4are as defined in the claims.
REFERENCES:
patent: 5232939 (1993-08-01), Terada et al.
patent: 5932576 (1999-08-01), Anantanarayan et al.
patent: 6156766 (2000-12-01), Arita et al.
patent: 6214807 (2001-04-01), Zablocki et al.
patent: 6352989 (2002-03-01), Miyazaki et al.
patent: 6448281 (2002-09-01), Beaulieu et al.
patent: 6664395 (2003-12-01), Letavic et al.
patent: 6710054 (2004-03-01), Nakao et al.
patent: 6770634 (2004-08-01), Zablocki et al.
patent: 6897230 (2005-05-01), Fukuda et al.
patent: 2001/0044445 (2001-11-01), Bamaung et al.
patent: 2002/0012946 (2002-01-01), Belardinelli et al.
patent: 2002/0077329 (2002-06-01), Audoly et al.
patent: 2003/0078232 (2003-04-01), Elzein et al.
patent: 2003/0092749 (2003-05-01), Dombroski et al.
patent: 2003/0125367 (2003-07-01), Fukuda et al.
patent: 656359 (1995-06-01), None
patent: 791594 (1997-08-01), None
patent: 58-41897 (1983-03-01), None
patent: WO 96/03385 (1996-02-01), None
patent: WO 96/20954 (1996-07-01), None
patent: WO 98/41090 (1998-09-01), None
patent: WO 98/52940 (1998-11-01), None
patent: WO 98/52941 (1998-11-01), None
patent: WO 00/31063 (2000-06-01), None
patent: WO 00/78778 (2000-12-01), None
patent: WO 01/62979 (2001-08-01), None
patent: WO 02/14321 (2002-02-01), None
patent: WO 2003051833 (2003-06-01), None
patent: WO 2003070723 (2003-08-01), None
Zablocki, J. et al., “2-Substituted Pi System Derivatives of Adenosine That Are Coronary Vasodilators” Nucleosides, Nucleotides & Nucleic Acids, vol. 20(4-7): 343-360 (Apr.-Jul. 2001)(available on-line Mar. 31, 2001) at p. 350, Table 4 (cmpd 31 “CVT-3033”).
Zhenhai Gao, et al., “Novel Short-Acting A2A Adenosine Receptor Agonists for Coronary Vasodilation,” J. Pharmacology and Experimental Therapeutics, vol. 298:209-218 (Jul. 2001) at p. 218 lines 37-38 (CVT-3033), lines 39-40 (CVT-3032), lines 46-47 (CVT-3126).
Magn. Reson. Chem., vol. 34, No. 4, pp. 318-323 (1996), Cudero, J. et al.
Chemical Abstracts, vol. 120, abs. No. 54498, Jonas, R. et al.
Chemical Abstracts, vol. 119, abs. No. 8730, Awad, IMA.
Chemical Abstracts, vol. 117, abs. No. 13117, Awad, IMA.
Phosphorus Sulfur Silicon Relat. Elem., vol. 66, No. 1-4, pp. 29-35 (1992), Ismail, N. et al.
Tetrahedron Lett., vol. 32, No. 50, pp. 7415-7418 (1991), Hamamichi, N.
Indian J. Chem., Sect. B, vol. 30B, No. 3, pp. 371-374 (1991), Essawy, S.A.
Chemical Abstracts, vol. 114, abs. No. 207112, Awad, I. M. A.
Chem. Pham. Bull., vol. 38, No. 7, pp. 2018-2019 (1990), Hamamichi, N. et al.
Mosmann et al., The Journal of Immunology, vol. 136, No. 7, 2348-2357, Apr. 1, 1986.
Darnell, Jr. et al., Science, vol. 264, 1415-1421, Jun. 3, 1994.
Quelle et al., Molecular and Cellular Biology, vol. 15, No. 6, 3336-3343, Jun. 1995.
Izuhara et al., The Journal of Biological Chemistry, vol. 271, No. 2, 619-622, Jan. 12, 1996.
T. Akimoto et al., J. Exp. Med., vol. 187, No. 9, 1537-1542, May 4, 1998.
D. Kuperman et al., J. Exp. Med., vol. 187, No. 6, 939-948, Mar. 16, 1998.
Kamata Jun-ichi
Miyamoto Mitsuaki
Miyazaki Futoshi
Ohashi Yoshiaki
Sakuma Yoshinori
Birch & Stewart Kolasch & Birch, LLP
Eisai Co. Ltd.
Paviglianiti Anthony J.
Saeed Kamal A.
LandOfFree
Nitrogen-containing condensed cyclic compound having a... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Nitrogen-containing condensed cyclic compound having a..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nitrogen-containing condensed cyclic compound having a... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3583211