Nitroderivatives of cardiovascular agents

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S369000, C514S400000, C548S188000, C548S201000, C548S338100

Reexamination Certificate

active

11234084

ABSTRACT:
Compounds or their salts having general formulas (I) and (II) wherein: s=is an integer equal to 1 or 2, preferably s=2; b0=0 or 1; A is the radical of a drug and is such as to meet the pharmacological tests reported in the description, C and C1are two bivalent radicals. The precursors of the radicals B and B1are such as to meet the pharmacological test reported in the description.

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Silverstein et al., “Misoprostol Reduces Serious Gastrointestinal Complications in Patients with Rheumatoid Arthritis Receiving Nonsteroidal Anti-Inflammatory Drugs”, Ann. Intern. Med, 123(4), 241-249, 1995.
Martindale: The Extra Pharmacopoeia; Thirty-first Edition, 73, 1966.
Current Medical Diagnosis & Treatment, 37thEd., 431 and 794, 1998.

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