Nitro and amino substituted topoisomerase agents

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C546S048000, C546S070000, C544S233000, C514S248000, C514S285000, C435S184000

Reexamination Certificate

active

06989387

ABSTRACT:
The invention provides compounds of formula I:wherein R1–R9, W, and X have any of the meanings defined in the specification and their pharmaceutically acceptable salts. The invention also provides pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I, and therapeutic methods for treating cancer using compounds of formula I.

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