Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1995-09-12
1998-08-04
Burn, Brian M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
514642, A61K 3140
Patent
active
057894477
ABSTRACT:
The present invention provides a method for treating oxygen free radical induced tissue damage associated with ischemia reperfusion injury, wherein nitric oxide is delivered to target cells/tissues through the administration of a nitric oxide-containing compound that spontaneously releases nitric oxide under physiological conditions without requiring the presence of oxygen.
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patent: 5714511 (1998-02-01), Saavedra et al.
Carey et al., Circulatory Shock, 38, 209-216 (1992).
Lefer et al., J. Cardiovasc. Pharmacol., 22 (Suppl. 7), S27-S33 (1993).
Lefer et al., Circulation, 88 (5 (1)), 2337-2350 (1993).
Masini et al., Biol. Nitric Oxide, Proc. 2nd Int. Meet. (Moncada, ed.), 1, 190-192 (1992).
Granger Daniel Neil
Grisham Matthew B.
Hanbauer Ingeborg
Krishna Murali C.
Mitchell James B.
Burn Brian M.
The Board of Supervisors of Louisiana State University and Agric
The United States of America as represented by the Department of
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