Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2002-02-13
2010-02-02
Hartley, Michael G (Department: 1618)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C514S252140, C514S565000
Reexamination Certificate
active
07655423
ABSTRACT:
There is provided a method of promoting neurogenesis by administering a therapeutic amount of a nitric oxide donor compound to a patient in need of neurogenesis promotion. Also provided is a compound for providing neurogenesis having an effective amount of a nitric oxide donor sufficient to promote neurogenesis. A nitric oxide compound for promoting neurogenesis is also provided. Further, a method of augmenting the production of brain cells and facilitating cellular structural and receptor changes by administering an effective amount of a nitric oxide donor compound to a site in need of augmentation is provided. There is provided a method of increasing both neurological and cognitive function by administering an effective amount of a nitric oxide donor compound to a patient.
REFERENCES:
patent: 4439196 (1984-03-01), Higuchi
patent: 4447224 (1984-05-01), DeCant, Jr. et al.
patent: 4447233 (1984-05-01), Mayfield
patent: 4475196 (1984-10-01), LaZor
patent: 4486194 (1984-12-01), Ferrara
patent: 4487603 (1984-12-01), Harris
patent: 4666828 (1987-05-01), Gusella
patent: 4683202 (1987-07-01), Mullis
patent: 4801531 (1989-01-01), Frossard
patent: 4925678 (1990-05-01), Ranney
patent: 4959217 (1990-09-01), Sanders et al.
patent: 5167616 (1992-12-01), Haak et al.
patent: 5169383 (1992-12-01), Gyory et al.
patent: 5192659 (1993-03-01), Simons
patent: 5225182 (1993-07-01), Sharma
patent: 5272057 (1993-12-01), Smulson et al.
patent: 5385940 (1995-01-01), Moskowitz
patent: 5428070 (1995-06-01), Cooke et al.
patent: 6262024 (2001-07-01), Cunningham et al.
patent: 6423751 (2002-07-01), Liao
Poluha et.al J. of biological Chem. vol. 272(38) pp. 24002-24007.
Kaposzta (Circulation. 2001;103:2371-2375).
Ohtsuka et al. The American J. of Med. vol. 108, (5) 2000, 439.
Quast et al., Brain research 677(20 1995, 204-212.
Horackova et al. Am. J. Physiol. Cell 269(2) Abstract only, 1995.
Jeremy et al. British J. Urology 1997, 79, 958-963.
Endres et al., Pro. Natl, Aca. Sci, 95; pp. 8880-8885, 1998.
Ausubel et al.,Current Protocols in Molecular Biology, John Wiley and Sons, Baltimore, Maryland (1989).
Burke and Olson, Methods in Enzymology, vol. 194, “Preparation of Clone Libraries in Yeast Artificial-Chromosome Vectors”, eds. C. Guthrie and G. Fink, Academic Press, Inc., Chap. 17, pp. 251-270, 1991.
Capecchi, MR. “Altering the genome by homologous recombination”, Science 244:1288-1292, 1989.
Davies, NP., Rosewell, IR., Brüggemann, M. “Targeted alterations in yeast artificial chromosomes for interspecies gene transfer”, Nucleic Acids Research, vol. 20, No. 11, pp. 2693-2698, 1992.
Dickinson, P., Kimber, WL., Kilanowski, FM., Stevenson, B.J., Porteous, DJ., Dorin, Jr. “High frequency gene targeting using insertional vector”, Human Molecular Genetics, vol. 2, No. 8, pp. 1299-1302, 1993.
Duff and Lincoln. “Insertion of a pathogenic mutation into a yeast artificial chromosome containing the human APP gene and expression in ES cells”, Research Advances in Alzheimer's Disease and Related Disorders, 1995.
Huxley, C., Hagino, Y., Schlessinger, D., Olson, MV. “The human HPRT gene on a yeast artificial chromosome is functional when transferred to mouse cells by cell fusion”, Genomics, 9:742-750 1991.
Innis MA, Gelfan DH, Sninsky JJ, White TJ, (eds.) “PCR Protocols: A Guide to Methods and Applications,” Academic Press, San Diego, CA 1990.
Jakobovits, A., Moore, AL., Green, LL., Vergara, GJ., Maynard-Currie, CE., Austin, HA., Klapholz, S. “Germ-line transmission and expression of a human-derived yeast artificial chromosome”, Nature, vol. 362, pp. 255-261, 1993.
Johnson, S., Bird, RE. “Construction of single-chain Fvb derivations of monoclonal antibodies and their production ofEscherichia coli”, Methods in Enzymology (JJ Langone, ed.; Academic Press New York, NY) 203:88-99, 1991.
Lamb et al. “Introduction and expression of the 400 kilobaseprecursor amyloid proteingene in transgenic mice”, Nature Genetics, vol. 5, pp. 22-29, 1993.
Mernaugh and Mernaugh. “An overview of phage-displayed recombinant antibodies”, Molecular Methods In Plant Pathology (RP Singh and US Singh, eds.; CRC Press Inc., Boca Raton, FL) pp. 359-365, 1995.
Mishell, BB., Shiigi, SM. Selected Methods in Cellular Immunology, W.H. Freeman and Company, New York, 1981.
Sambrook et al.,Molecular Cloning: A Laboratory Manual, Cold Spring Harbor Laboratory Press, New York (1989).
Testoni N, Martinelli G, Farabegoli P, Zaccaria A, Amabile M, Raspadori D, Pelliconi S, Zuffa E, Carboni C, Tura S. “A New Method of “In-Cell Reverse Transcriptase-Polymerase Chain Reaction” for the Detection of BCR/ABL Transcript in Chronic Myeloid Leukemia Patients,” Blood, vol. 87, No. 9, 3822-3827, May 1, 1996.
Chopp Michael
Zhang Rui Lan
Gembeh Shirley V
Hartley Michael G
Henry Ford Health System
LandOfFree
Nitric oxide donors for inducing neurogenesis does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Nitric oxide donors for inducing neurogenesis, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nitric oxide donors for inducing neurogenesis will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4190220