Nimesulide gel systems for topical use

Details Nimesulide gel systems for topical use Nimesulide gel systems for topical use

2007-03-06

2007-03-06

Kim, Vickie (Department: 1618)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

C514S769000, C514S887000, C424S078050, C424S449000

Reexamination Certificate

active

10254862

ABSTRACT:
The present invention relates to nimesulide topical formulations comprising a carboxyvinylpolymer neutralized as a gel-forming agent or a polyacrylamide-isoparaffin and a solvent selected from the group consisting of ethanol, isopropanol and diethylene glycol monoethyl ether, and to the process for the preparation thereof. Said formulations have advantages such as higher stability of the system and bioavailability of the active ingredient.

REFERENCES:
patent: 5716609 (1998-02-01), Jain et al.
patent: 5837735 (1998-11-01), Miyata et al.
patent: 0 532 900 (1993-03-01), None
patent: 0 812 587 (1997-12-01), None
patent: 9611002 (1996-04-01), None
patent: WO 98/01124 (1998-01-01), None
Chemical Abstracts, vol. 125, No. 4, Jul. 22, 1996, (abstract only) WIPO patent WO 9611002A Dec. 1997.
Chemical Abstracts, Database WPI/Derwent AN:97-225967 (abstract only) WIPO patent WO 9712608, Apr. 1997.

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