Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Food or edible as carrier for pharmaceutical
Patent
1993-12-20
1996-06-11
Marquis, Melvyn I.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Food or edible as carrier for pharmaceutical
424434, 424435, 424439, A61K 920
Patent
active
055253512
ABSTRACT:
A saliva-soluble stimulant unit comprising an active ingredient and optional ingredients comprising flavor and aroma additives incorporated in a gel prepared by gelling a water-binding gelling agent, in which the active ingredient comprises nicotine or other alkaloids with the same direction of activity, said unit having i) a texture profile, determined by texture profile analysis, with parameter values of firmness, hardness, brittleness, adhesiveness, elasticity, and cohesiveness within given ranges; (ii) a disintegration time within the range 5-60 minutes; and (iii) a nicotine content from 0.5 to 10 mg or a corresponding content of said alkaloids.
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Declaration of Henning Gjelstrup Kristensen.
Appendeix A--Curriculum Vitae--Henning Gjelstrup Kristensen.
European Pharamacopoeia, Second Edition, part II, 1992.
USP XXII; NF XVII; The United States Pharmacopeia, The National Formulary, 1990.
Martindale, The Extra Pharmacopoeia; 26th Edition, Norman W. Blacow, ed. p. 739.
Remington's Pharmaceutical Sciences, 18th Edition, Mack Publishing Company, p. 1664.
Harrison Robert H.
Marquis Melvyn I.
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