Nickel-based reagents for detecting DNA and DNA-protein...

Chemistry: analytical and immunological testing – Peptide – protein or amino acid

Reexamination Certificate

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C436S094000, C530S300000, C530S400000, C534S010000, C534S012000, C536S025400, C540S145000

Reexamination Certificate

active

07371579

ABSTRACT:
The invention relates to a compound comprising a labeled nickel complex (FIG.1) that is used to detect and purify nucleic acid sequences by forming an adduct between a specific nucleic acid base and the labeled nickel complex. The adduct can also be purified through a separation process, such as affinity chromatography

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