New sulfated diosmin derivative

Details New sulfated diosmin derivative New sulfated diosmin derivative

1993-02-25

1994-03-22

Cintins, Marianne M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514926, 514927, 514928, 536 8, 536 88, 536 171, 536 181, 536118, A61K 3170, C07H 1100, C07H 1500, C07H 1524

Patent

active

052964698

ABSTRACT:
The diosmin heptakis (hydrogensulfate) aluminum complex is described, as l as its preparation procedure, characterized by reacting one mole of diosmin with seven moles of a sulfating agent in a dry medium and treatment with an aqueous aluminum hydroxycloride solution of the diosmin heptakis (hydrogensulfate) sodium salt thus obtained. A description of pharmacological assays carried out to confirm the cytoprotective action of the product is included.

REFERENCES:
patent: 4334058 (1982-06-01), Nair et al.
patent: 4414207 (1983-11-01), Nair et al.
patent: 4894449 (1990-01-01), Venero et al.

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