Chemistry: analytical and immunological testing – Hemoglobin – myoglobin – or occult blood
Patent
1985-07-02
1990-10-30
Raymond, Richard L.
Chemistry: analytical and immunological testing
Hemoglobin, myoglobin, or occult blood
436135, 436904, 422 58, 435 28, 435807, 548235, 546 23, 546 94, 546172, 546174, 546176, 544 82, 544 84, 544 85, 544 87, 544137, G01N 3372, C12Q 128, C07D26330
Patent
active
049668552
ABSTRACT:
The invention provides new redox indicators and uses for these redox compounds (I): ##STR1## Wherein X is oxygen or sulphur, R.sub.1 is julolidine or tetrahydroquinoline, which can carry an alkyl radical on the nitrogen atom which, in turn, can be substituted by a sulphuric, phosphonic or carboxylic acid residues, or is (II); wherein R.sub.4 is hydroxyl or a mono- or dialkylated amino group, R.sub.5 and R.sub.6, which can be the same or different, are hydrogen, alkyl or alkoxy, R.sub.2 is hydrogen or alkyl, julolidine or tetrahydroquinoline, which can carry an alkyl on the nitrogen atom which alkyl can be substituted by sulphuric, phosphonic or carboxylic acids, or is III; wherein R.sub.5 and R.sub.6 are the same as in R.sub.1 and R'.sub.4 is hydroxyl, an amino or a mono-or dialkylated amino group, whereby the alkyl radicals can be substituted one or more times by hydroxyl, alkoxy, halogen, morpholine or a sulphuric, carboxylic or phosphonic acid residue, which acids can also be esterified, and R.sub.3 is the same as R.sub.2 or is an alkyl substituted by hydroxyl, alkoxy, dialkylamino or phenyl, or is cycloalkyl, phenyl or pyridyl; as well as the salts thereof.
REFERENCES:
patent: 3630957 (1971-12-01), Rey et al.
patent: 4089747 (1978-05-01), Brushi
patent: 4220713 (1980-09-01), Rittersdorf et al.
patent: 4312834 (1982-01-01), Vogel et al.
patent: 4477575 (1984-10-01), Vogel et al.
patent: 4604264 (1986-08-01), Rothe et al.
Deneke Ulfert
Guthlein Werner
Weckerle Wolfgang
Wielinger Hans
Boehringer Mannheim GmbH
Covington Raymond
Raymond Richard L.
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