New platinum complex

Details New platinum complex New platinum complex

1978-09-12

1980-04-29

Sneed, Helen M. S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260429R, 424287, C07D30922, C07D30928

Patent

active

042005833

ABSTRACT:
Cis-platinum (II) complexes wherein platinum (II) coordinates 1,2-diamino-cyclohexane (cis-, trans-l- or trans-d-) are disclosed. The complexes exhibit anti-tumor activity.

REFERENCES:
patent: 3712948 (1973-01-01), Halpern et al.
patent: 3904663 (1975-09-01), Tobe et al.
patent: 4115418 (1978-09-01), Gale et al.
Leh et al., J. of Pharmaceutical Sciences, 65(3), pp. 315-320 (1976).
Schwartz et al., Cancer Treatment Reports, 61 No. 8, pp. 1519-1525 (1977).
Meischen et al., J. Natl. Cancer Inst. 57(4), pp. 841-845 (1976).
Ward et al., Cancer Treatment Reports 60(11), pp. 1675-1678 (1976).

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