New physiologically active substance, arphamenine and production

Details New physiologically active substance, arphamenine and production New physiologically active substance, arphamenine and production

1985-12-16

1989-08-22

Warren, Charles F.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing nitrogen-containing organic compound

435822, C12P 1300

Patent

active

048595934

ABSTRACT:
New physiologically active substances, arphamenine A and arphamenine B which are generically termed arphamenine are produced from a new microorganism, BMG361-CF4 strain identified as FERM P-6521 or FERM BP-286 or ATCC No. 39373. Arphamenine is useful as a host defence stimulator having an activity to enhance cell-mediated immunity, and also as an anti-tumor agent.

REFERENCES:
Sykes et al., "Monocyclic .beta.-Lactam Antibiotics produced by Bacteria", Nature, vol. 291, pp. 489-491, 1981.
Umezawa et al., Chemical Abstracts, vol. 100, No. 175262, 1983.

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