New pentapeptides and methods for their production

Details New pentapeptides and methods for their production New pentapeptides and methods for their production

1976-06-23

1977-08-23

Phillips, Delbert R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2601125R, 424177, C07C10352

Patent

active

040439933

ABSTRACT:
New pentapeptides having the formula X-R-Tyr-(benzyl)-Ser(benzyl)-R.sup.1 -Y wherein X is t-butoxycarbonyl or benzyloxycarbonyl, R is a single amino acid fragment, a dipeptide fragment or tripeptide fragment utilizing amino acids selected from the group consisting of Pro, Aze, His-(benzyl) and Trp; R.sup.1 is a single bond or a single amino acid fragment or a dipeptide fragment utilizing amino acids selected from the group consisting of Ala, Trp and His and Y is lower alkoxy, hydrazino, amino, lower alkylamino or di(lower alkyl)amino with the proviso that the total number of amino acid units when R and R.sup.1 are combined is three.

REFERENCES:
patent: 3796697 (1974-03-01), Flouret
Biochem. and Biophys. Res. Comm. (1974) 57, 1248-1256.
Biochem. and Biophys. Res. Comm. (1974) 60, 406-412.

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