New glycoprotein and process for isolating it

Details New glycoprotein and process for isolating it New glycoprotein and process for isolating it

1979-12-19

1981-05-26

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Lymphokine

260112R, 260112B, 424101, A61K 3900, C07G 700

Patent

active

042698251

ABSTRACT:
A new glycoprotein is characterized by a protein consisting essentially of 75.+-.6% of .alpha.-amino-acids, a carbohydrate portion of 24.6.+-.5.2%, which contains 8.9.+-.2% of hexoses, 7.1.+-.1.5 of N-acetylated hexosamine, 0.2.+-.0.2% of fucose, 8.4.+-.1.5% of, N-acetylated neuraminic acid; a sedimentation coefficient S.sub.20w of 2.5.+-.0.3 S; a molecular weight of 35,000.+-.5,000, determined in the ultracentrifuge, and a molecular weight of 65,000.+-.10,000, determined in polyacrylamide gel containing sodium dodecyl sulfate; an iso-electric point at pH 3.4.+-.0.4; an extinction coefficient E.sub.1.sup.1%.sub.cm (280 nm) of 1.9.+-.0.3; an electrophoretic mobility in the range between that of .alpha..sub.1 and .alpha..sub.2 -globulins; and a specific immunologic reaction with an antibody specifically directed against the glycoprotein.

REFERENCES:
Bohn, H., Protides Biol. Fluids, 24, pp. 117-124, (1976).
Bohn, H., Arch. Gynaekol, vol. 212, pp. 165-175, (1972).
Bohn, H., Blut, vol. 24, pp. 292-302, (1972).
Bohn, H., Arch. Gynaekol, vol. 221, pp. 73-81, (1976).
Bohn, H., Arch. Gynaekol, vol. 218, pp. 131-142, (1975).

Affiliated with

Also associated with

Rating

New glycoprotein and process for isolating it does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with New glycoprotein and process for isolating it, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and New glycoprotein and process for isolating it will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-453443