New derivatives of 2,4,6-triiodo-isophthalic acid, proceses for

Details New derivatives of 2,4,6-triiodo-isophthalic acid, proceses for New derivatives of 2,4,6-triiodo-isophthalic acid, proceses for

1980-07-30

1982-09-07

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Molecular bilayer structure

564153, A61K 4904

Patent

active

043483771

ABSTRACT:
Novel, radio-opaque compounds comprising water-soluble bis-[N-{3,5-bis-(hydroxyalkylaminocarbonyl)-2,4,6-triiodo-phenyl}-N-(.alph a.-hydroxyacyl)-amino]-alkanes are disclosed for use as X-ray contrast agents. These compounds are relatively simple to synthesize, possess low toxicity and have good stability as well as resistance to hydrolysis. Methods for preparation and use of the compounds are also disclosed.

REFERENCES:
patent: 3632738 (1972-01-01), Ingelman
patent: 3678152 (1972-07-01), Bjork et al.
patent: 4239747 (1980-12-01), Pfeiffer et al.
patent: 4250113 (1981-02-01), Nordal et al.

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