New benzoic acid derivatives, as well as processes for their pro

Details New benzoic acid derivatives, as well as processes for their pro New benzoic acid derivatives, as well as processes for their pro

1987-05-22

1988-10-18

Reamer, James H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

562459, 562473, C07C10134

Patent

active

047789255

ABSTRACT:
Para substituted benzoic acid derivatives of general formula (1) ##STR1## and their physiologically compatible salts, where R.sup.1 may be H, isopropyl, t-butyl p0 X may be ##STR2## and R.sup.2 may be --OH, --OR', where R' is a linear or branched, saturated or unsaturated C.sub.1 to C.sub.3 alkylmoiety, or a --NHCH.sub.2 COOH-- group, have hypolipedemic activity. They may be obtained by known methods either from the corresponding unsaturated ketones or from saturated hydroxycompounds, where the esterified benzoic acid moiety may be saponified or converted to a carboxymethylamide.

REFERENCES:
patent: 4067892 (1978-01-01), Thorne et al.
patent: 4073935 (1978-02-01), Grill et al.
patent: 4154850 (1979-05-01), Morgan et al.
patent: 4189594 (1980-02-01), Grill et al.
patent: 4582857 (1986-04-01), Grill et al.

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