New 3-(hydroxybenzylidenyl)-indolin-2-ones

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514339, 514256, 514414, 548486, 548466, 548467, 548468, 546273, 544333, C07D20934

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active

053825934

ABSTRACT:
The invention relates to a compound selected from those of formula (I): ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5 and X are as defined in the description, its Z and E isomers, its optical isomers, in pure form or in the form of a mixture, and its addition salts thereof with a pharmaceutically-acceptable acid or base, and medicinal products containing the same which are useful in treating a disorder resulting from or associated with peroxidation phenomena, disturbances in eicosanoid synthesis, or with platelet aggregation disorders.

REFERENCES:
patent: 5124347 (1992-06-01), Connor et al.
Valentine et al. CA 119(11): 117181b. 1992.
Zhungietn et al. CA 78: 111201w 1973.
Nakanishi CA 117(9): 90138n. 1992.
English Abstract of JP 62029570 (1985).
WPIL Derwent Report showing that the Japanese patent has not been extended to other countries.

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