New 3-formylrifamycin SV derivatives

Details New 3-formylrifamycin SV derivatives New 3-formylrifamycin SV derivatives

1974-10-23

1976-01-20

Jiles, Henry R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424244, 424250, 424263, 424267, 424272, 424274, 424275, 424278, C07D49104, C07D52100

Patent

active

039338002

ABSTRACT:
The present invention is concerned with new derivatives of 3-formylrifamycin SV. More particularly the invention relates to O-substituted oximes of 3-formylrifamycin SV of formula I. ##SPC1##
wherein R is selected from the group consisting of alkyl of at least 2 carbon atoms, alkenyl, alkynyl, cycloalkyl, alkoxyalkyl, cycloalkoxyalkyl, hydroxyalkyl, carboxyalkyl, carboalkoxyalkyl, carbamylalkyl, cyanoalkyl, nitroalkyl, aryloxyalkyl, aralkoxyalkyl, heterocycloxyalkyl, aminoalkyl, mono- and di-lower alkylaminoalkyl, substituted benzyl, mono- or poly-aryl substituted C.sub.2 -C.sub.8 alkyl and lower alkyl substituted with mono- or polynuclear heterocyclic rings containing at least one 1 to 3 heteroatom selected from oxygen, nitrogen and sulfur, with the exclusion of morpholine; R.sub.1 is H or CH.sub.3 CO; and the derivatives of the same oximes hydrogenated in at least one of the positions 16, 17; 18, 19; and 28, 29. These compounds have antimicrobial activity.

REFERENCES:
patent: 3342810 (1975-09-01), Maggi et al.

Affiliated with

Also associated with

Rating

New 3-formylrifamycin SV derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with New 3-formylrifamycin SV derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and New 3-formylrifamycin SV derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1696804