Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 15 to 23 amino acid residues in defined sequence
Patent
1993-08-16
1996-12-24
Weimar, Elizabeth C.
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
15 to 23 amino acid residues in defined sequence
530327, A61K 3800, A61K 3702, C07K 706, C07K 1400
Patent
active
055874576
ABSTRACT:
The present invention provides peptides capable of stimulating neutrophils. In particular, the peptides prime neutrophils for a respiratory burst following treatment with N-formyl-L-methionyl-L-leucyl-Lphenylalanine. The peptides have an amino acid sequence substantially corresponding to amino acids 54 to 94 of FIG. 1 or a part thereof. These peptides may also be used in the treatment of a subject having depressed neutrophil function.
REFERENCES:
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Ferrante Antonio
Rathjen Deborah A.
Marshall S. G.
Peptide Technology Limited
Weimar Elizabeth C.
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