Neutrophil stimulating peptides

Details Neutrophil stimulating peptides Neutrophil stimulating peptides

1996-09-17

2000-09-19

Russel, Jeffrey E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 14, 514 15, A61K 3808, A61K 3810, A61K 3816

Patent

active

061212377

ABSTRACT:
The present invention provides peptides capable of stimulating neutrophils. In particular, the peptides prime neutrophils for a respiratory burst following treatment with N-formyl-L-methionyl-L-leucyl-L-phenylalanine. The peptides have an amino acid sequence substantially corresponding to amino acids 54 to 94 of FIG. 1 or a part thereof. These peptides may also be used in the treatment of a subject having depressed neutrophil function.

REFERENCES:
patent: 5587457 (1996-12-01), Rathjen et al.

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