Neutrophil inhibitors

Details Neutrophil inhibitors Neutrophil inhibitors

1994-05-24

1998-01-13

Ulm, John

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

530417, 424520, 514 8, C07K 200, A61K 3556

Patent

active

057081417

ABSTRACT:
Compositions enriched for Neutrophil Inhibitory Factor which inhibit neutrophil activity including adhesion to vascular endothelial cells are provided. Such compositions may comprise a glycoprotein isolated from nematodes, particularly of the genus Ancylostoma. These compositions are useful in the therapy of conditions which involve abnormal or undesired inflammatory responses.

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