Neutralizing monoclonal antibody against botulinum neurotoxin se

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Animal cell – per se – expressing immunoglobulin – antibody – or...

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435 7021, 4351722, 5303884, 5303873, 4241641, 4242471, C12N 512, A61K 39395

Patent

active

058077413

ABSTRACT:
Antibodies which neutralize botulinum neurotoxin serotype F are produced using biologically active botulinum neurotoxin instead of toxoid for immunization and exploiting the importance of cross reaction between various serotypes to obtain immune responses, or monoclonal antibodies, to additional serotypes of interest. Methods of preparation and uses of the neutralizing botulinum neurotoxin antibodies are described.

REFERENCES:
Paul, WE. 1993 Fundamental Immunology p.242.

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