Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving viable micro-organism
Patent
1995-03-06
1997-08-12
Leary, Louise
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving viable micro-organism
435 4, 435 26, 435 6, 435968, 435975, 436 94, 436800, 536 231, 536 2673, 536 111, 536 256, C12Q 104, C12Q 100, C12Q 132, G01N 3353
Patent
active
056564490
ABSTRACT:
The invention describes the preparation and use of fluorescent stains for nucleic acids derived from neutral unsymmetrical cyanine dyes comprising a substituted benzazolium ring system linked to a methine bridge to a pyridine or quinoline ring system. The fluorescence characteristics of the dyes when complexed with nucleic acids give the dyes utility for the detection of oligonucleotides and nucleic acids in cells, gels and solutions. The dyes have particular utility in the staining of reticulocytes.
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Helfenstein Allegra J.
Leary Louise
Molecular Probes, Inc.
Skaugset Anton E.
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