Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1993-02-01
1994-11-08
Nutter, Nathan M.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
536103, C07G 300, C07G 1100, C07H 1500, A01N 4340
Patent
active
053628608
ABSTRACT:
A solid composition for stabilizing the dosage of cognition activator CI-979 HCl by formation of a complex with cyclic polydextrose. In particular, compositions with HP.beta.CD have been found to stabilize CI-979 HCl even in the presence of other excipients such as sodium carbonate. Pharmaceutical formulations for the treatment of cognitive disorders in humans are based on the stabilizing composition of CI-979 HCl and cyclic polydextrose, including appropriate amounts of other excipients or components as known in the formulation art.
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Fawzi Mahdi B.
Huang Hua-pin
Julian Thomas N.
Radebaugh Galen W.
Wootton Scott C.
Atkins Michael J.
Nutter Nathan M.
Warner-Lambert & Company
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