Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Patent
1988-10-31
1992-11-24
Russel, Jeffrey E.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
530416, 530417, 530848, A61K 3702, C07K 302, C07K 312, C07K 1506
Patent
active
051663171
ABSTRACT:
Novel neutrotrophic factor compositions are provided, obtained from lung tissue. The factors are found to be active on parasympathetic ganglion neutrons enhancing acetylcholine activity. The compositions find use in the treatment of a number of eye disorders.
REFERENCES:
patent: 4923696 (1990-05-01), Appel et al.
patent: 4997929 (1991-03-01), Collins et al.
patent: 5011914 (1991-04-01), Collins et al.
Chemical Abstracts 109:67650f (1988), abstracting Hofmann, "Ciliary neuronotrophic factor stimulates choline acetyltrasferase activity in cultured chicken retina neurons", J. Neurochem., 1988, 51(1), 109-13.
Angeletti, et al., "Subunit Structure and Amino Acid Composition of Mouse Submaxillary Gland Nerve Growth Factor", Biochemistry, vol. 10, No. 3 (1971) pp. 463-469.
Lin, et al., "Purification, Cloning and Expression of Ciliary Neurotrophic Factor (CNTF)", Research Articles, Nov. 24, 1989, pp. 1023-1025.
Levi-Montalcini, Science (1987) 237:1154-1162.
Barde, et al., EMBO Journal (1982) 1:549-553.
Gaspodarowicz, et al., Proc. Natl. Acad. Sci. USA (1984) 81:6963-6967.
Barbin, et al., Journal of Neurochemistry (1984) 43:1468-1478
Weber, et al., Journal of Neurochemistry (1985) 45:1541-1547.
Fukada, Proc. Natl. Acad. Sci. USA (1985) 82:8795-8799.
Manthorpe, et al., Developmental Brain Research (1986) 25:191-198.
Wallace, et al., Brain Research (1986) 375:92-101.
Gurney, et al., Science (1986) 234:566-574.
Watters, et al., Journal of Neurochemistry (1987) 49:705-713.
Unsicker, et al., Proc. Natl. Acad. Sci. USA (1987) 84:5459-5463.
Wallace, et al., Brain Research (1987) 411:351-363.
Dal Toso, et al., The Journal of Neuroscience (1988) 8:733-745.
McManaman, et al., The Journal of Biological Chemistry (1988) 263:5890-5897.
Anderson, et al., Nature (1988) 332:360-361.
Crosson Craig E.
Potter David E.
Wallace Thomas L.
Houston Biotechnology Incorporated
Rea-Venter Barbara
Russel Jeffrey E.
LandOfFree
Neurotrophic factor does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Neurotrophic factor, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Neurotrophic factor will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-922690