Neurotoxins with enhanced target specificity

Details Neurotoxins with enhanced target specificity Neurotoxins with enhanced target specificity

2007-08-02

2008-11-25

Navarro, Mark (Department: 1645)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C435S069100, C435S069700, C435S071100, C435S071200, C435S252300, C435S252330, C435S320100, C536S023400

Reexamination Certificate

active

07456272

ABSTRACT:
Modified neurotoxins that contain protease cleavage sites susceptible uniquely to proteases present in certain tissues are described. The toxins can be selectively activated by proteases in muscle or selectively inactivated by proteases in blood.

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