Neurotherapeutic azole compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C514S281000, C514S283000, C548S250000, C548S255000, C548S262200

Reexamination Certificate

active

07598279

ABSTRACT:
Azole compounds containing carbamoyl group and pharmaceutically useful salts thereof are described. The compounds are effective anticonvulsants which are used in the treatment of disorders of the central nervous system, especially as anxiety, depression, convulsion, epilepsy, migraine, bipolar disorder, drug abuse, smoking, ADHD, obesity, sleep disorder, neuropathic pain, stroke, cognitive impairment, neurodegeneration, stroke and muscle spasm.

REFERENCES:
patent: 3415840 (1968-12-01), Wolf
patent: 5100916 (1992-03-01), Johansson et al.
patent: 6770659 (2004-08-01), Choi et al.
patent: WO 2006/112685 (2006-10-01), None
International Search Report issued for the corresponding PCT application No. PCT/KR2006/001523.
Written Opinion of the International Search Report issued for the corresponding PCT application No. PCT/KR2006/001523.
Karakurt et al., “Synthesis of some 1-(2-naphthyl)-2-(imidazole-1-yl)ethanone oxime and oxime ether derivatives and their anticonvulsant and antimicrobial activities,” Eur. J. Med. Chem. May 2001; 36(5): 421-433.

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