Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1992-06-02
1997-12-09
Ketter, James
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 696, 435 694, 435 6952, 4351723, 4352544, 4353201, 435219, 536 241, C12P 2102
Patent
active
056959656
ABSTRACT:
Neurospora crassa transformations are employed for production of heterologous proteins, where DNA constructs are prepared using a foreign gene under transcriptional and translational regulatory regions functional in Neurospora. A functional signal sequence is provided for secretion of the heterologous gene product. An auxotrophic Neurospora host is employed and transformed by the combination of the subject construct and a complementing gene. The resulting transformants provide for efficient secretion of the heterologous product.
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Ivy John M.
Koo Kenneth
Stuart W. Dorsey
Hawaii Biotechnology Group, Inc.
Ketter James
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