Neuroprotective macrocyclic compounds and methods for their use

Details Neuroprotective macrocyclic compounds and methods for their use Neuroprotective macrocyclic compounds and methods for their use

2004-03-16

2009-02-03

Wilson, James O. (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C540S476000

Reexamination Certificate

active

07485630

ABSTRACT:
Embodiments of this invention provide novel peptidomimetics that contain a macrocycle. Such compounds are neuroprotective and have utility as therapeutic agents for treatment of diseases, injuries and other conditions characterised by neuronal degeneration and/or death. Compounds are also useful for manufacture of medicaments useful for treatment of such conditions.

REFERENCES:
patent: PCT/US04/08108 (2004-03-01), None
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Belvisi, et al., “Conformational Preferences of Peptides Containing Reverse-Turn Mimetic Bicyclic Lactams: Inverse y-Turns versus Type-II B-Turns”.
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