Neuroprotective effect of growth hormone

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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C514S003100, C514S004300, C514S012200, C530S399000

Reexamination Certificate

active

09786982

ABSTRACT:
The invention relates to neuroprotection and to medicaments for use therein. Neuroprotection is induced by activation of neural growth hormone receptors, primarily using medicaments comprising growth hormone, growth hormone analogs or ligands which are functionally equivalent. Such medicaments may also include one or more secondary neuroprotective agents.

REFERENCES:
patent: 4939124 (1990-07-01), Cacabelos
patent: 5468726 (1995-11-01), Cacabelos
patent: 5736515 (1998-04-01), Bengtsson
patent: 2003/0049838 (2003-03-01), Thompson et al.
patent: 757907 (2003-06-01), None
patent: 0720483 (1993-09-01), None
patent: WO 99/33481 (1999-07-01), None
patent: WO 00/13650 (2000-03-01), None
patent: WO 03/24471 (2003-03-01), None
Rudinger, InPeptide Hormones, Ed. J. A. Parsons, University Park Press, Baltimore, pp. 1-7, 1976.
Burman et al,Clinical Endocrinology, vol. 44, pp. 319-324, 1996.
Nyberg et al.Horm. Res. vol. 45, pp. 18-22, 1996.
Golab et al.Endokrynologia Polska, vol. 14, pp. 233-237, 1963.
Golab et al.Endokrynologia Polska, vol. 14, pp. 233-237, 1963. (English Translation).
Phelps, C.J., “Stimulatory Effect of Human, But Not Bovine, Growth Hormone Expression on Numbers of Tuberoinfundibular Dopaminergic Neurons in Transgenic Mice,”Endocrinology, Baltimore, Maryland, 1977, Vo. 138, No. 7, pp. 2849-2855.
Chen, L. et al., “Growth Hormone, Insulin-like Growth Factor I, and Motoneuron Size,”Journal of Neurobiology, 1997, vol. 32, No. 2, pp. 202-212.
Scheepens, A., et al., “Alterations in the Neural Growth Hormone Axis Following Hypoxic-Ischemic Brain Injury,”Molecular Brain Research, Elsevier Science BV, Amsterdam, Netherlands, 1999, vol. 68, pp. 88-100.
Scheepens, A., et al., “Growth Hormone as a Neuronal Rescue Factor During Recovery from CNS Injury,”Neuroscience, Jun. 14, 2001, vol. 104, No. 3, pp. 677-687.
Clark, Ross G. and Iain Robinson, “Up and Down the Growth Hormone,”Cytokine&Growth Factor Reviews, 1996, vol. 7, No. 1, pp. 65-80.
Lobie, Peter E.; García Aragòn, Juanita; Lincoln, David T.; Barnard, Ross; Wilcox, Josiah N.; and Waters, Michael J., “Localization and Ontogeny of Growth Hormone Receptor Gene Expression in the Central Nervous System,”Developmental Brain Research, Elsevier Science Publishers B.V., 1993, vol. 74, pp. 225-233.
Loccick, Sarah A.; Xin-Jun Liu; Lu, Zi-Xian; Liu, Changlu; Behan, Dominic P.; Chalmers, Derek C.; Foster, Alan C.; Vale, Wylie W.; Ling, Nicholas; and De Souza, Errol B., “Displacement of Insulin-like Growth Factors from Their Binding Proteins as a Potential Treatment for Stroke,”Pharmacology, The National Academy of Sciences, Feb. 1998, vol. 95, pp. 1894-1898.
L. Chen, et al., “Growth Hormone, Insulin-like Growth Factor I, and Motoneuron Size”, Dept. of Physiology and Curriculum in Neurobiology, N.C., Sep. 25, 1996, pp. 202-212.
Anatomy, Tulane Univ. School of Medicine, Endocrinology, vol. 138, No. 7, pp. 2849-2855, 1997.
R. Clark, et al., “Up and Down the Growth Hormone Cascade”, Cytokine & Growth Factor Reviews, vol. 7, No. 1, pp. 65-80, 1996.
Pharmacology, vol. 95, pp. 1894-1898, Feb. 1998.
P. E. Lobie, et al., “Localization and ontogeny of growth hormone receptor gene expression in the central nervous system”, Developmental Brain Research, 74 (1993) 225-233.

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