Neuroprotection by indolactam V and derivatives thereof

Details Neuroprotection by indolactam V and derivatives thereof Neuroprotection by indolactam V and derivatives thereof

1991-11-27

1994-03-08

Hollrah, Glennon H.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

540460, 548433, A01N 4390, C07D48702

Patent

active

052927652

ABSTRACT:
A method for reducing adverse effects of neurotoxic injury, which comprises administering to a patient susceptible to neurotoxic injury an effective amount, sufficient to reduce the injury, of a compound having an indolactam V ring system. Particularly preferred are compounds having ring stereochemistry as indicated in the following formula: ##STR1## The indicated substituents show preferred locations of substituents; preferred substituents are defined in the specification.

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