Neuropeptide control of ocular growth

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert

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424422, 424423, 424428, 514 12, 514 21, 514912, 514929, 530324, 530843, 530844, A61F 200, A61K 3700, A61K 3702

Patent

active

050553020

ABSTRACT:
A method and composition for inhibition of abnormal postnatal ocular growth are disclosed. The composition comprises vasoactive intestinal peptide (VIP), PHI or a analogue of these peptides. The method for inhibition of abnormal postnatal ocular growth comprises administering to the eye of an animal effective amount of VIP, PHI or analogue of these peptides.

REFERENCES:
patent: 3862927 (1975-01-01), Said et al.
patent: 4745100 (1988-05-01), Gilbard et al.
Increase in Retinal VIP After Eyelid Fusion in Primates, Stone et al., PNAS, , 257, 1988.
Different Effects of Substance P and VIP on the Motor Function of Bovine Intraocular Muscles, Suzuki et al., Invest. Ophthalmol. Vis. Sci., 24, 1566, 1983.

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