Neuronal bHLH-PAS domain proteins

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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435440, 435455, 435471, 435325, 4352523, 536 235, C12N 120, C12N 1500, C12N 1511

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active

058405321

ABSTRACT:
The invention provides methods and compositions relating to neuronal PAS domain proteins (NPAS) and related nucleic acids. The proteins may be produced recombinantly from transformed host cells from the disclosed NPAS encoding nucleic acids or purified from human cells. The invention provides isolated NPAS hybridization probes and primers capable of specifically hybridizing with the disclosed NPAS gene, NPAS-specific binding agents such as specific antibodies, and methods of making and using the subject compositions in diagnosis, therapy and in the biopharmaceutical industry.

REFERENCES:
GenBank Accession No. R67292 Submitted by Hillier et al., The WashU-Merck EST Project; 30 May 1995.
GenBank Accession No. U51628 Submitted by J. Hoganesch; 1 Dec. 1996.

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