Neuron-restrictive silencer factor nucleic acids

Details Neuron-restrictive silencer factor nucleic acids Neuron-restrictive silencer factor nucleic acids

1995-03-03

1999-08-10

Caputa, Anthony C.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

4353201, 435325, 536 231, 536 235, C07H 2100, C12N 510, C12N 1563, C12P 2102

Patent

active

059358114

ABSTRACT:
The present invention relates to neuron-restrictive silencer factor proteins, nucleic acids, and antibodies thereto.

REFERENCES:
Vandenbergh, D.J., et al., "Chromatin structure as a molecular marker of cell lineage and developmental potential in neural crest-derived chromaffin cells", Neuron, 3:507-518, (1989).
Stein, R., et al., "The NGF-Inducible SCG10 mRNA Encodes a Novel Membrane-Bound Protein Present in Growth Cones and Abundant in Developing Neurons", Neuron, 1:463-476 (1988).
Wuenschell, C.W., et al., "Analysis of SCG10 Gene Expression in Transgenic Mice Reveals that Neural Specificity Is Achieved through Selective Derepression", Neuron, 4:595-602 (1990).
Mori, N., et al., "A Cell Type-Preferred Silencer Element That Controls the Neural-Specific Expression of the SCG10 Gene", Neuron, 4:583-594, (1990).
Schoenherr, C.J., et al., "The Neuron-Restrictive Silencer Factor (NRSF): A Coordinate Repressor of Multiple Neuron-Specific Genes", Science, 267:1360-1363 (1995).
Maue, R.A., et al., "Neuron-Specific Expression of the Rat Brain Type II Sodium Channel Gene Is Directed by Upstream Regulatory Elements", Neuron, 4:233-231 (1990).
Kraner, S.D., et al., "Silencing the Type II Sodium Channel Gene: A Model for Neural-Specific Gene Regulation", Neuron, 9:37-44, (1992).
Chong, J.A., et al., "REST: A Mammalian Silencer Protein That Restricts Sodium Channel Gene Expression to Neurons", Cell, 80:949-957 (1995).
Mori, N., et al., "A Common Silencer Element in the SCG10 and Type II Na+ Channel Genes Binds a Factor Present in Nonneuronal Cells but Not in Neuronal Cells", Neuron, 9:45-54 (1992).
Sauerwald, Angela, et al., "The 5'-Flanking Region of the Synapsin I Gene--A G+C-Rich, TATA-and CAAT-Less, Phylogenetically Conserved Sequence with Cell Type-Specific Promoter Function," J. Biol. Chem. 265(25):14932-14937 (Sep. 5, 1990).
Schoenherr, C.J., et al. "Mouse Neural Restrictive Silencer Factor," EMBL, Accession Number: Mm13878 (Jul. 1, 1995).
Krieg, P.A., et al. "Gene Activation in Response to Neural Induction," Cellular and Molecular Biology Research, 39:377-383 (1993).
Chowdhury et al., Nucleic Acids Res., vol. 16, pp. 9995-10,011, 1988.
Reeck et al., Cell, vol. 50, p. 667, 1987.

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