Neuromuscular relaxants

Details Neuromuscular relaxants Neuromuscular relaxants

1997-10-24

1999-11-23

Davis, Zinna Northington

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514305, 514316, 546126, 546133, 546186, C07D40102, A61K 3146

Patent

active

059901241

ABSTRACT:
Alkoxy and/or acyloxy disubstituted and polysubstituted aralkyl and aralkenyl bis-quaternary ammonium derivatives of cyclic alkanol diesters have neuromuscular relaxant properties.

REFERENCES:
patent: 2734062 (1956-02-01), Hotovy et al.
patent: 2746964 (1956-05-01), Biel et al.
patent: 5494898 (1996-02-01), Cheng et al.
Gyermek, L. and Nador, K., The Pharmacology of Tropane Compounds in Relation to their Steric Structure, The Journal of Pharmacy and Pharmacology, 1957, 9, pp. 209-229.
Haining, C,G., Johnston, R.G., Smith, J.M., The Neuromuscular Blocking Properties of a Serial of Bis-Quaternary Tropeines, Brit. J. Pharmacol., 1960, 15, pp. 71-81.
Nador, K., Gyermek, L., Attempts to Find New Compounds with Curare-Like Effects, Part III. Quaternary Derivatives of Dicarboxylic Tropine Esters, Acta Chimica Hung., 1952, pp. 369-374.

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