Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Patent
1992-02-26
1992-10-20
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
424422, 424423, 424484, 424486, 6048901, 6048911, A61F 200, A61K 922
Patent
active
051568446
ABSTRACT:
Neurological therapy devices are disclosed for the local and controlled delivery of a neurotransmitter to the brain of a subject suffering from neurotransmitter deficiency or dysfunction. In one embodiment the device includes a biocompatible, implantable, and retrievable polymeric insert including a source of neurotransmitter embedded therein. In another embodiment, the device includes a retrievable source of neurotransmitter including at least one neurotransmitter-secreting cell encapsulated within a semipermeable membrane allowing the diffusion therethrough of the neurotransmitter, and further includes a source of growth factor in close proximity to the neurotransmitter-secreting cells.
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Aebischer Patrick
Winn Shelley R.
Brown University Research Foundation
Engellenner Thomas J.
Kishore G. S.
Page Thurman K.
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