Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1991-02-27
1992-10-20
Berch, Mark L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514211, 540524, 544230, 544349, 546326, C07D48704, C07D21160, C07D21162, A61K 31495
Patent
active
051570343
ABSTRACT:
Antipsychotic compounds having the formula ##STR1## wherein Z is H or Cl; Y is O or S; n is 1-4; separately, X is H or (C.sub.1 -C.sub.2)alkyl and L is R(CH.sub.2).sub.m CO, m is 0 or 1-3, R is (C.sub.1 -C.sub.6)alkyl, (C.sub.3 -C.sub.7)cycloalkyl, phenyl, naphthyl, furyl, benzofuranyl, thienyl, benzothienyl, pyrrolyl, indolyl, isoindolyl or one of said groups substituted on aromatic or heteroaromatic ring with fluoro, chloro, (C.sub.1 -C.sub.2)alkyl or (C.sub.1 -C.sub.2)alkoxy; or together L and X, in combination with the nitrogen to which they are attached, form certain cyclic imides, 4-substituted piperidines or a cyclic sulfonamide.
REFERENCES:
patent: 4681938 (1987-07-01), Traxler
patent: 4831031 (1989-05-01), Lowe, III et al.
patent: 4957916 (1990-09-01), Kennis et al.
Bright Gene M.
Desai Kishor A.
Seeger Thomas F.
Berch Mark L.
Lumb J. Trevor
McFarlin D. Stuart
Pfizer Inc.
Richardson Peter C.
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