Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Patent
1995-05-25
1999-01-12
Myers, Carla J.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
536 235, 536 2431, 435 691, 530828, 935 9, C07K 14435, C07H 2104
Patent
active
058591958
ABSTRACT:
The entire coding region of the gene involved in von Recklinghausen neurofibromatosis (NF1) and a ubiquitously expressed large transcript (NF1LT) of the gene have been identified, cloned and sequenced. With the identification of the NF1 gene and its gene product, nucleic acid probes and antibodies raised to the gene product can be used in a variety of hybridization and immunological assays to screen for NF1 and detect it in its early stages. Conventional and gene therapies can also be developed to treat those afflicted with the disease.
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Andersen Lone B.
Collins Francis S.
Gutmann David H.
Marchuk Douglas A.
Wallace Margaret R.
Myers Carla J.
The Regents of the University of Michigan
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