Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Testing efficacy or toxicity of a compound or composition
Reexamination Certificate
2006-06-13
2006-06-13
Priebe, Scott D. (Department: 1633)
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
Testing efficacy or toxicity of a compound or composition
C800S008000
Reexamination Certificate
active
07060249
ABSTRACT:
A method for obtaining aDrosophilaneurodegeneration mutant includes the steps of selecting at least oneDrosophilamutant having an aberrant phenotype selected from the group consisting of temperature-sensitive paralysis and bang-sensitive paralysis; and screening the at least one selectedDrosophilamutant for age-dependent neurodegeneration. Neurodegeneration mutants are obtained in the method and causal mutations are characterized. The neurodegeneration mutants can be used in screening methods to identify putative neuroprotective agents.
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Norman DJ, Feng L, Cheng SS, Gubbay J, Chan E, Heintz N
Ganetzky Barry S.
Palladino Michael J.
Priebe Scott D.
Quarles & Brady LLP
Wisconsin Alumni Research Foundation
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