Neuroactive substance and uses of one such substance

Details Neuroactive substance and uses of one such substance Neuroactive substance and uses of one such substance

2004-11-25

2010-11-23

Andres, Janet L (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C514S475000

Reexamination Certificate

active

07838695

ABSTRACT:
The invention relates to a neuroactive substance which is characterised in that it has formula (O), wherein R1, R2, R3 and R4 are identical or different and are methyl or ethyl radicals. Preferably, the neuroactive substance comprises 6S-acetyl-4R,5R-dimethyl-1R(10S)-epoxy-2R-hy-droxy-7R-acetoxydecahydro naphthalene which can be isolated fromRhytisma fulvumcnidaria. The inventive neuroactive substance can be used as a pharmacological reagent in research work and is also suitable for use in the fields of industry (insecticides) and health.

REFERENCES:
L.A. Morris et al.: “A bioactive secosterol with an unusual A- and B-ring oxygenation pattern isolated from an Indonesian soft coralLobophytum sp.”, Journal of Natural Products, 1998, vol. 61, No. 4, pp. 538-541.
D. Green et al.: “Secondary metabolites of the yellow and gray morphs of the soft coralParerythropodium fulvum fulvum: Comparative aspects”, Journal of Natural Products (Lloydia), 1992, vol. 55, No. 9, pp. 1186-1196.
S. Naz et al., “New antiproliferative epoxysecosterols fromPseudopterogorgia americana”, Tetrahedron Letters, 2000, vol. 41, No. 32, pp. 6035-6040.

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